Document Type : Original Research Article
Authors
1 Chemistry Department, Faculty of Science, University of Benghazi, Benghazi, Libya
2 Chemistry Department, Faculty of Arts and Science, Elmergib University, Al-khoms, Libya
Abstract
The current research aims to develop a new spectrophotometric method for the determination of zinc(II) and copper(II) using a colorimetric reagent, as murexide ion. The complexation of Zn(II) and Cu(II) with murexide has been studied spectrophotometrically at absorption maxima of 450 and 470 nm for Zn-murexide and Cu-murexide, respectively. The murexide reagent interacts with Zn(II) and Cu(II) instantaneously at pH 7 and pH 5.5, respectively, and the absorbance of the solution is stable for 220 and 120 minutes, respectively. Using Job’s continuous variation method, the stoichiometry of the complexes was found to be 1:2 metal to ligand ratio for Zn and Cu, respectively. The continuous variation approach was used to estimate the stability constants (Kstab) values, which were found to be in the order 1.35x1016 and 2.30x107 for Zn and Cu complexes, respectively. The proposed spectrophotometric methodology established that zinc(II) and copper(II) could be estimated at levels of 0.2-2.0 and 0.5-5.0 ppm, which has molar absorptivity values of 1.95x104 and 6.55x103 l.mol-1.cm-1, respectively. Likewise, the formed complexes were stable at different pH values, allowing the simultaneous estimation of the two metals.
Graphical Abstract
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Keywords
Main Subjects
[1] B. Wang, Z. Bai, H. Jiang, P. Prinsen, R. Luque, S. Zhao, J. Xuan, Selective heavy metal removal and water purification by microfluidically-generated chitosan microspheres: Characteristics, modelling and application. Journal of Hazardous Materials, 364 (2019) 192–205. https://doi.org/10.1016/j.jhazmat.2018.10.024.
[2] V. Karri, D. Ramos, J.B. Martinez, A. Odena, E. Oliveira, S.L. Coort, C.T. Evelo, E.C.M. Mariman, M. Schuhmacher, V. Kumar, Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity. Journal of Proteomics, 187 (2018) 106–125.
[3] B. Kumar, S. Das, 1,3-Dimethylvioluric acid as a colorimetric chemosensor for the selective detection of Fe3+ metal ion in aqueous medium. Chemical Data Collections, 35 (2021) 100750.
[4] V.K. Gupta, L.P. Singh, R. Singh, N. Upadhyay, S.P. Kaur, B. Sethi, A novel copper (II) selective sensor based on Dimethyl 4, 4′ (o-phenylene) bis(3-thioallophanate) in PVC matrix. Journal of Molecular Liquids, 174 (2012) 11–16.
https://doi.org/10.1016/j.molliq.2012.07.016.
[5] V.K. Gupta, A.K. Singh, L.K. Kumawat, Thiazole Schiff base turn-on fluorescent chemosensor for Al3+ ion. Sensors and Actuators B: Chemical, 195 (2014) 98–108.
https://doi.org/10.1016/j.snb.2013.12.092.
[6] V.K. Gupta, S. Kumar, R. Singh, L.P. Singh, S.K. Shoora, B. Sethi, Cadmium (II) ion sensing through p-tert-butyl calix[6]arene based potentiometric sensor. Journal of Molecular Liquids, 195 (2014) 65–68.
[7] K.M. Elsherif, A. El-Hashani, I Haider, Equilibrium and Kinetic Studies of Cu (II) Biosorption Onto Waste Tea and Coffee Powder (WTCP). Iranian Journal of Analytical Chemistry, 5 (2018) 31-38.
[8] E. Raafid, M.A. Al-Da’amy1, S.H. Kadhim, Spectrophotometric Determination of Cu(II) in Analytical Sample Using a New Chromogenic Reagent (HPEDN). Indonesian Journal of Chemistry, 20 (2020) 1080–1091. DOI: 10.22146/ijc.47894
[9] J.A. Khdeeja, A.M. Layla, J.A. Fatima, N.R. Haider, New spectrophotometric determination of copper(II) using an organic reagent derived from imidazole and 4-aminoantypyrine and applied onto different samples. Journal of Chemical and Pharmaceutical Sciences, 8 (2015) 201–207.
[10] S. Seidi, L. Alavi, Novel and rapid deep eutectic solvent (DES) homogeneous liquid–liquid micro-extraction (HLLME) with flame atomic absorption spectrometry (FAAS) detection for the determination of copper in vegetables. Analytical Letters, 52 (2019) 2092–2106.
[11] Q. Yang, G.P. Tang, L.F. Tian, Q.L. Wei, C. Wang, Determination of trace copper in vanadium alloy by flame atomic absorption spectrometry. Advanced Materials Research, 1120-1121 (2015) 1395–1398.
[12] K.M. Elsherif, H-M. Kuss, Direct and Simultaneous Determination of Bismuth, Antimony, and Lead in Biological samples by Multi-Element Electrothermal Atomic Absorption Spectrometer. Der Chemica Sinica, 3(2012) 727-736.
[13] M. Karadjov, N. Velitchkova, O. Veleva, S. Velichkov, P. Markov, N. Daskalova, Spectral interferences in the determination of rhenium in molybdenum and copper concentrates by inductively coupled plasma optical emission spectrometry (ICP-OES). Spectrochimica Acta, Part B, 119 (2016) 76–82.
[14] K.M. Elsherif, H.M. Kuss, Simultaneous Multi-Element Determination of Bismuth (Bi), Antimony (Sb), and Selenium (Se). Advances in Applied Science Research, 3 (2012) 2402-2412.
[15] M. Pięk, K. Fendrych, J. Smajdor, R. Piech, B. Paczosa-Bator, High selective potentiometric sensor for determination of nanomolar con-centration of Cu(II) using a polymeric electrode modified by graphene/7,8,8-tetracyanoquinodimethane nanoparticles. Talanta, 170 (2017) 41–48.
[16] G. Scarano, E. Morelli, A. Seritti, A. Zirino, Determination of copper in seawater by anodic stripping voltammetry using ethylenediamine. Analytical Chemistry, 62 (1990) 943–948.
[17] S. Ohno, M. Tanaka, N. Teshima, T. Sakai, Successive determination of copper and iron by a flow injection-catalytic photometric method using a serial flow cell. Analytical Sciences, 20 (2004) 171–175.
[18] M.Q. Al-Abachi, S.S. Abed, N.A. Al-Najjar, A new chromogenic reagent for determination of copper(II) in water samples using flow injection-technique. Iraqi Journal of Science, 58 (2017) 201–210
[19] K.P. Satheesh, S. Ravichandran, V.S. Rao, Spectrophotometric determination of Cu (II) and Ni (II) using 4-hydroxybenzaldehyde thiosemicarbazone. International Journal of ChemTech Research, 3 (2011) 2062–2065.
[20] I. Gaubeur, M.C. da CunhaAreias, L.H.S. Avila Terra, M.E.V. Suarez-Iha, Spectrophotometric Determination of Zinc in Pharmaceutical Samples using Di-2-Pyridyl Ketone Salicyloylhydrazone. Spectroscopy Letters, 35(2002) 455–465. http://dx.doi.org/10.1081/SL-120005678
[21] R. Lobinski, Z. Marczenko, Recent Advances in Ultraviolet-Visible Spectrophotometry. Critical Reviews in Analytical Chemistry, 23 (1992) 55.
[22] A.M. Ali, M.A. Al-Da`amy, A.F. Kadhier, R.S. Hatam, Synthesis of 2-[(3-chloro-4,6-disulfanamide phenyl) azo] -4,5–diphenyl imidazole (Cdsai) as a new analytical reagent for the determination of Cu(II). Iraqi National Journal Of Chemistry, 37 (2010) 66–73.
[23] S.H. Kadhim, I.Q. Abd-Alla, T.J. Hashim, Synthesis and characteristic study of Co(II), Ni(II) and Cu(II) complexes of new Schiff base derived from 4-aminoantipyrine. International journal of chemical science, 15 (2017) 107–114.
[24] S. Zareba, Spectrophotometric Determination of Zinc in Multivitamin Pharmaceutical Preparations with the Use of Azo Dyes Series 1,2,4- Triazole (Metriarez-Gamma) and Benzimidazole (BIAR). Die Pharmazie, 49 (1994) 659.
[25] M.S. Masoud, T.S. Kassem, M.A. Shaker, A.E. Ali, Studies on Transition Metal Murexide Complexes. Journal of Thermal Analysis and Calorimetry, 84 (2006) 549-555. https://doi.org/10.1007/s10973-005-9991-3
[26] K. Grudpan, J. Jakmunee, Y. Vaneesorn, S. Watanesk, U. A. Maung and P. Sooksamiti, Flow-injection spectrophotometric determination of calcium using murexide as a color agent. Talanta, 46 (1998) 1245-1257. https://doi.org/10.1016/S0039-9140(97)00410-4
[27] K.M. Elsherif, A. Zubi, A. Najar, H. Bin Ghashir, Complexation of Pyrazole Based Ligands with Ag (I): Spectrophotometric Studies in Mixed Solvent (EtOH-H2O). Arabian Journal of Chemical and Environmental Research, 8 (2021) 236–246
[28] T. K. Khan, P. B. Gupta, Accurate values of stability constant of Ca2+-murexide complex. Talanta, 44 (1997) 2087. https://doi.org/10.1016/S0039-9140(97)00078-7
[29] Y.T. Nakamura, H. Shata, M. Minao, H. Ogawa, N. Sekiguchi, M. Murata, S. Homma, Isolation of a Zinc-chelating Compound from Instant Coffee by the Tetramethyl Murexide Method. LWT - Food Science and Technology, 27 (1994) 115-118. https://doi.org/10.1006/fstl.1994.1026
[30] J. Ghasemi, M. Shamsipur, A kinetic study of complex formation between calcium ion and cryptand C221 in dimethylsulphoxide solution. Polyhedron, 15 (1996) 923-927. https://doi.org/10.1016/0277-5387(95)00311-1
[31] K.M. Elsherif, F.M. Nabbra, A. M. Ewlad-Ahmed, N. Elkebbir, Spectrophotometric Complex Formation Study of Murexide with Nickel and Cobalt in Aqueous Solution. To Chemistry Journal, 5 (2020) 40-47.
[31] C.T. Adedibu, A.O. Joshua, K.O. Gabriel, Spectrophotometric Study of Stability Constants of Dapsone–Cu(II) Complex at Different Temperatures. Journal of Pharmacy Research, 4 (2011) 241–244
[32] K.M. Elsherif, A. Zubi, H.B. Shawish, S.A. Abajja, E.B. M. Almelah, Complex Formation of Bis(salicylidene)ethylenediamine (Salen type ligand) with Cupper(II) Ions in Different Solvents: Spectrophotometric and Conductometric Study, International Journal of New Chemistry, 7 (2020) 1-13.
[33] K.M. Elsherif, A. Zubi, A. Najar, E. Bazina, Complexation of 1,4-bis (3-(2-pyridyl) pyrazol-1-ylmethyl) benzene (1,4-PPB) with Cu (II), Co (II), and Ni (II): Spectrophotometric Studies in Mixed Solvent (EtOH-H2O). To Chemistry Journal, 1 (2018) 214-223
[34] H.M. Alabidi, A.M. Farhan, M.M. Al-Rufaie, Spectrophotometric Determination of Zn(II) in Pharmaceutical Formulation Using a New Azo Reagent as Derivative of 2-Naphthol. Current Applied Science and Technology 21 (2021) 176-187.
[35] M.R. Fathi, M. Shamsipur, Spectrophotomictric Study of Zinc, Cadmium and Lead Complexes with Murexide in Binary Ethanol-Water Mixtures. Spectroscopy Letters, 26 (1993) 1797-1804.
[36] A. Reiss, A. Samide, G. Ciobanu, I. Dăbuleanu, Synthesis, spectral characterization and thermal behavior of new metal(II) complexes with Schiff base derived from amoxicillin. Journal of the Chilean Chemical Society, 60 (2015) 3074–3079.
[37] T. Mihelj, V. Tomašić, N. Biliškov, F. Liu, Temperature-dependent IR spectroscopic and structural study of 18-crown-6 chelating ligand in the complexation with sodium surfactant salts and potassium picrate. Spectrochimica. Acta, Part A, 124 (2014) 12–20.
[38] 11. Shamsipur and N. Alizadeh, Spectrophotometric study of cobalt, nickel, copper, zinc, cadmium and lead complexes with murexide in dimethylsulphoxide solution. Talanta, 39 (1992) 1209-1212.
[39] C.L. Sethi, B.K. Puri, M. Satake, Spectrophotometric Determination of Zinc, Cadmium, and Lead after Extraction of their Morpholine-4-carbodithioates into Molten Naphthalene and Replacement by Copper. Microchemical Journal, 33 (1986) I79- 189.
[40] S.A. Tirmizi, M.H.S. Wattoo, S. Sarwar, W. Anwar, F.H. Wattoo, A.N. Memon, J. Iqbal, 2009, Spectrophotometric study of stability constants of famotidine-Cu(II) complex at different temperatures. Arabian Journal for Science and Engineering, 34 (2009) 43–48.
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