Document Type : Review Article


1 Associate Professor of Cardiac Anesthesia, Department of Anesthesiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

2 Assistant Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran


Background: Since the minimum effective dose of the two drugs bupivacaine and Ropivacaine has not been included in the anesthesia reference books and different doses have been suggested for the drugs in the current study, as well as in previous studies, these drugs are combined with other drugs have been used, which affect the side effects and length of anesthesia, in this systematic review study on the hemodynamic changes of patients who are candidates for elective cesarean surgery by spinal anesthesia using two Bupivacaine and Ropivacaine drugs should be evaluated at the minimum dose in terms of low hemodynamic disorders, side effects and anesthesia, and suggest the appropriate drug in this field. Methodology: In this review article, all databases including Google Scholar, Scopus, Web of Science, PubMed, SID, MagIran, and the Cochrane Library were searched and reviewed by both authors of this article based on PRIZMA guidelines without time and language limitations.
Results: So that the percentage of blood pressure drop in bupivacaine group patients was 50% higher than Ropivacaine group with 23%, and in other words, it can indicate more stability of blood pressure in Ropivacaine group. Conclusion: Based on this study, statistically, the rate of systolic blood pressure drop, the need for ephedrine, as well as the incidence of nausea and vomiting in patients receiving Ropivacaine were lower, which are important when anesthetizing people with hemodynamic instability, such as pregnant women with Valvular cardiomyopathy can be important.

Graphical Abstract

Investigating the Hemodynamic Responses of Women Candidates for Elective Cesarean Section to Two Drugs, Bupivacaine and Ropivacaine: a Systematic Review


Main Subjects

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