Progress in Chemical and Biochemical Research

Phytochemical constituents, antioxidant activity and antimicrobial potential of Pulicaria incisa (lam.) DC as a folk medicinal plant

Omar El-Shahaby; Mustafa El-Zayat; Reham Rabei; Heshmat Soliman Aldesuquy

Volume 2, Issue 4 , November 2019, , Pages 222-227

https://doi.org/10.33945/SAMI/PCBR.2019.4.7

Abstract

The species belonging to the genus Pulicaria are well known for their traditional uses in folklore medicine, active chemical constituents and pharmacological activities. Therefore, ... Read More

Thermal Conductivity and Anisotropy of Intermolecular Potential Energy in Refrigerant Fluids R125, R134a, R12, R14 and R141b

fahimeh Moeini; tayebeh hosseinnejad; fatemeh sadat Alavi

Volume 4, Issue 4 , December 2021, , Pages 426-439

https://doi.org/10.22034/pcbr.2021.312188.1200

Abstract

Refrigerant fluids are widely used to reduce temperature in heat transfer systems and study of the thermal conductivity of these fluids is of great importance in design of heat transformers, ... Read More

Synthesis of liponucleotides using bacterial phospholipase D

Larisa Birichevskaya; Margarita Vinter; Natalia Litvinko; Anatoli Zinchenko

Volume 3, Issue 1 , February 2020, , Pages 64-73

https://doi.org/10.33945/SAMI/PCBR.2020.1.8

Abstract

A series of conjugates of pharmacologically promising modified nucleosides with phospholipid was synthesized. Some liponucleotides were originally produced. Soybean lecithin served ... Read More

Risk Management in Oil and Gas Refineries

Amir samimi

Volume 3, Issue 2 , May 2020, , Pages 140-146

https://doi.org/10.33945/SAMI/PCBR.2020.2.8

Abstract

This study examines why risk management is required in the energy industry. The variability of competitive laws in the world of business and energy has been highlighted as a major policy ... Read More

Sex Determination in Papaya: A mini review

Vaghela Foram; Kariya Pooja; Vijay R. Ram; Pragnesh N Dave

Volume 2, Issue 4 , November 2019, , Pages 228-234

https://doi.org/10.33945/SAMI/PCBR.2019.4.8

Abstract

There is an intriguing system for sex determination in Carica Papaya. To explain the genetics of the Papaya’s sex determination there were many hypotheses based on information ... Read More

Extraction and Antibacterial Studies of Oil from three Mango Kernel obtained from Makurdi - Nigeria

Kaana Asemave; D. O. ABAKPA; T.T. LIGOM

Volume 3, Issue 1 , February 2020, , Pages 74-80

https://doi.org/10.33945/SAMI/PCBR.2020.1.9

Abstract

The ability of bacteria to develop resistance to many antibiotics cannot be undermined given the multifaceted health challenges in the present times. For this reason a lot attention ... Read More

Comparative Assessment of Phytochemicals in Four (4) Varieties of Ananas Comosus (l.) Merr Peels

Tarhemba Terwanger Philip; Kaana Asemave; G.O Obochi

Volume 4, Issue 1 , January 2021, , Pages 1-10

https://doi.org/10.22034/pcbr.2020.240534.1111

Abstract

The paper reports comparative assessment of some phytochemicals in four (4) varieties of pineapple (Ananas comosus (L.) merr) peels / rinds. These varieties were Native Pineapple (A), ... Read More The paper reports comparative assessment of some phytochemicals in four (4) varieties of pineapple (Ananas comosus (L.) merr) peels / rinds. These varieties were Native Pineapple (A), Queens Pineapple (B), MD-2 Pineapple (C), and Smooth Cayene pineapple (D). The pineapples were collected, properly washed, and the peels were processed. After that, the peels were pulverized and oven-dried at 50 OC for 48 h. Chefman 500 W Blender was used to blend these dry samples into 0.5 µm sizes. The resulting peels were used for the analyses of alkaloid, tannin, phytate, oxalate, flavonoid, cardiac glycoside, total phenolic, and βeta- carotene using standard reported procedures. The results implied higher levels of flavonoid and total phenol in the varieties C and D than for the varieties A and B. The levels of β-carotene and cardiac glycoside were found to be significantly different (p <0.05) amongst the different peels. However, it was observed that there was no significant difference (p <0.05) in tannin and phytate contents of these rinds. There was also no significant difference in the oxalate contents of varieties A and B; but difference in the oxalate levels of varieties C and D was significant (p <0.05). Like the varieties A and B, the difference in alkaloids content of varieties C and D was not significant (p <0.05). These peels can be blended into our diets because of the presence of these phytochemicalsThe paper reports comparative assessment of some phytochemicals in four (4) varieties of pineapple (Ananas comosus (L.) merr) peels / rinds. These varieties were Native Pineapple (A), Queens Pineapple (B), MD-2 Pineapple (C), and Smooth Cayene pineapple (D). The pineapples were collected, properly washed, and the peels were processed. After that, the peels were pulverized and oven-dried at 50 OC for 48 h. Chefman 500 W Blender was used to blend these dry samples into 0.5 µm sizes. The resulting peels were used for the analyses of alkaloid, tannin, phytate, oxalate, flavonoid, cardiac glycoside, total phenolic, and βeta- carotene using standard reported procedures. The results implied higher levels of flavonoid and total phenol in the varieties C and D than for the varieties A and B. The levels of β-carotene and cardiac glycoside were found to be significantly different (p <0.05) amongst the different peels. However, it was observed that there was no significant difference (p <0.05) in tannin and phytate contents of these rinds. There was also no significant difference in the oxalate contents of varieties A and B; but difference in the oxalate levels of varieties C and D was significant (p <0.05). Like the varieties A and B, the difference in alkaloids content of varieties C and D was not significant (p <0.05). These peels can be blended into our diets because of the presence of these phytochemicals.

Copper Catalyzed Cycloaddition Reaction of Azidomethyl Benzene With 2,2-Di(prop-2-yn-1-yl)propane-1,3-diol: DFT and QTAIM Investigation

monireh ghiasifar; tayebeh hosseinnejad; Akram Ahangar

Volume 5, Issue 1 , February 2022, , Pages 1-20

https://doi.org/10.22034/pcbr.2022.319090.1203

Abstract

In this study, the cycloaddition of azidomethyl benzene with 2,2-di(prop-2-yn-1-yl)propane-1,3-diol in the presence of copper catalyst was modeled electronically and thermodynamically ... Read More

Effect Study of Verbena Ofﬁcinalis Medicinal Herb on Sex Hormones Level of NMRI Female Rats During Pregnancy

Yadolah Edalatpanah; marzieh avazzadeh; zainab abraheh; fariba enayatiparvar; reza bzorgyan; leila moradi jaferi; susan rostampour

Volume 6, Issue 1 , January 2023, , Pages 1-10

https://doi.org/10.22034/pcbr.2022.330897.1215

Abstract

The use of medicinal herbs in the treatment of diseases has become increasingly widespread, in this regard the Verbena ofﬁcinalis is considered as one of the herbs that affects pregnancy. ... Read More The use of medicinal herbs in the treatment of diseases has become increasingly widespread, in this regard the Verbena ofﬁcinalis is considered as one of the herbs that affects pregnancy. The present study was conducted to investigate the Verbena ofﬁcinalis herb on the level of sex hormones of NMRI female rats during pregnancy. This is an experimental study which divided 40 rats into 5 groups of 8 each and the groups included control, sham, and experimental with 5, 10, and 15 mM alcoholic extract of Verbena ofﬁcinalis. The serum levels measurement of FSH and LH hormones was done using ELISA (Biotech) method. After blood sampling, the ovaries were stained with hematoxylin eosin for histological examination. Cell count and thickness measurement of different ovarian cells, primitive follicles, primary follicles, growing follicles, graph follicles, lymph nodes, blood vessels, atretic follicles, and abnormal follicles (1 or 2 oocytes in one follicle) were examined microscopically in 6 segments of tissue segments from different groups. The statistical analysis was performed using SPSS23 software.The findings of the present study showed that the consumption of alcoholic extract of Verbena ofﬁcinalis significantly reduced the levels of LH, FSH, the number of abnormal follicles, the number of graph follicles, and the number of corpus luteum in the experimental group compared to the control group (p≤0.05), the number of primary follicles, the number of growing follicles, the number of ethereal follicles, and the number of blood vessels in the experimental group compared to the control group (p≤0.05). The weight, ovarian weight, ovarian diameter, secondary follicle diameter, and primary follicle diameter decreased in experimental groups compared to control group and sham group; however, this decrease was not significant and abnormal follicle diameter in experimental groups compared to control group and group. Sham increased but this increase was not significant (p> 0.05). The results of the present study show that consumption of Verbena ofﬁcinalis medicinal plant can be effective in abortion

A Comprehensive Review of Solvent-Induced Variability in Antioxidant Profiling of Plants Extract: Justicia secunda

Bulus Bako; Adi Hosea Danladi; Godiya Gambo Bulus; John Paul Shinggu

Volume 7, Issue 1 , January 2024, , Pages 1-21

https://doi.org/10.48309/pcbr.2024.417487.1292

Abstract

Variability in antioxidant profiles, particularly within plant extracts like Justicia secunda and other plant extracts, presents a significant challenge for researchers striving to ... Read More

Investigating the Feasibility of Removing Nitrogen and Phosphorus from Gray Water in Effluent Treatment to Reuse Water

Mahdieh Asgari Bajgirani

Volume 4, Issue 1 , January 2021, , Pages 11-19

https://doi.org/10.22034/pcbr.2021.118035

Abstract

Wastewater is the excess water flow caused by water consumption in various human activities that can contain various physical, chemical and biological pollutants and endanger human ... Read More

Combined QSAR Modeling, Molecular Docking Screening, and Pharmacokinetics Analyses for the Design of Novel 2, 6-Diarylidene Cyclohexanone Analogs as Potent Anti-Leishmanial Agents

Fabian Audu Ugbe; Gideon Adamu Shallangwa; Adamu Uzairu; Ibrahim Abdulkadir

Volume 6, Issue 1 , January 2023, , Pages 11-30

https://doi.org/10.22034/pcbr.2022.366493.1234

Abstract

The current research was conducted as part of the anti-leishmanial drug discovery effort towards new drug molecules with attributes that overcome the limitations of existing therapies. ... Read More

Application of Ziegler-Nata Catalysts in the Synthesis of Polyolefin

Mahdieh Asgari Bajgirani

Volume 4, Issue 1 , January 2021, , Pages 20-31

https://doi.org/10.22034/pcbr.2021.118046

Abstract

Discovering Ziegler-Nata catalyst, Karl Ziegler had a great impact on the development of the chemical industry. Since then, important changes have been made in the method of production ... Read More

Importance of forensic techniques in the investigation of rape (sodomy) and murder

Bhausaheb Parashuram More; Apurva D Deore; Maruti S Ghuge; Narendra R Gosavi; Sangita V Ghumatkar

Volume 5, Issue 1 , February 2022, , Pages 21-29

https://doi.org/10.22034/pcbr.2022.319031.1205

Abstract

The forensic DNA fingerprinting technique play a vital role during the investigation of rape and murder cases and gives strong scientific evidence for linking the suspect with the scene ... Read More

The Impact of Sodium Dodecyl Sulfate on Methane Hydrate Volume Fraction in a Batch Rocking Cell Reactor

Abolfazl Mohammadi

Volume 7, Issue 1 , January 2024, , Pages 22-33

https://doi.org/10.48309/pcbr.2024.421942.1301

Abstract

Natural gas holds significant importance as a prospective energy source for meeting growing energy demands in the future. Gas hydrates offer a solution for the transportation and storage ... Read More

The Effect of Drought Stress on Physiological Traits in Lines and Cultivars of Bread Wheat (Triticum aestivum L.)

Kamal Shahbazi Homounlou; Ali Ebadi; Salim Farzaneh; Manocher Khodarahmi

Volume 5, Issue 1 , February 2022, , Pages 30-43

https://doi.org/10.22034/pcbr.2022.326728.1211

Abstract

All around the globe, drought is considered one of the critical threats putting agricultural industries at stake. With such impediments existing, challenges of feeding the population ... Read More

‎Chalcone Derivatives Containing Imine Moieties as New Antibacterial Agents: Synthesis, SAR, Anti-biofilm Activity and Docking study

Ahmed Mutanabbi Abdula

Volume 6, Issue 1 , January 2023, , Pages 31-45

https://doi.org/10.22034/pcbr.2023.378340.1241

Abstract

A new series of 3-furan-2-yl-1-p-aryl-propenone derivatives containing imine moieties (1-7) were synthesized and characterized using spectral analysis. The synthesized derivatives were ... Read More

Fenton Processes, Adsorption and Nano Filtration in Industrial Wastewater Treatment

Moslem Shahamatpour; Seyed Mostafa Tabatabaee Ghomsheh; Sara Maghsoudi; Shima Azizi

Volume 4, Issue 1 , January 2021, , Pages 32-43

https://doi.org/10.22034/pcbr.2021.118152

Abstract

This paper reviews Fenton processes, adsorption and nano filtration processes. Wastewater is one of the substances that has been neglected even in recent years in the country. Industrial ... Read More

Theoretical Study of the Anticancer Properties of Iproplatin Drug and Comparison with Cis- Diamine- dichloro Platinum (II) (CDDP)

mohammad rizehbandi; zahra Moafi; masoud shojaee

Volume 7, Issue 1 , January 2024, , Pages 34-50

https://doi.org/10.48309/pcbr.2024.412451.1281

Abstract

Numerous transnational experimenters have strived to understand the medium of action or ameliorate the efficacy of inorganic collaboration composites that have been linked to parade ... Read More Numerous transnational experimenters have strived to understand the medium of action or ameliorate the efficacy of inorganic collaboration composites that have been linked to parade anticancer exertion. The essential challenges of chemotherapy demand that new strategies be developed utilizing different mechanisms of action to intrude the cellular ministry of cancer cells. In Australia, we have served from the exploration of associates who have told ultramodern platinum chemistry by contributing to our understanding of platinum oxidation and reduction, the medium of action of cisplatin, and unique design strategies for new platinum complexes. The purpose of this review is to give some backgrounds on the history and development of platinum (II) and platinum (IV) complexes. AS an anticancer drug, Iproplatin has a similar function as cis-diamine-dichloro platinum (II) (Cisplatin), but its toxicity varies and is usually lower. In this research, a comparison of anticancer drugs was performed based on cisplatin and its use in the design of newer drugs to determine the comparative index for measuring the drug potency of this category of compounds. In addition, using theoretical calculations, the process of combining iproplatin with the bases of adenine, thymine, cytosine, and guanine forming DNA and comparing it with cisplatin was investigated from the veiwpoint of thermodynamics and activation energy. The results showed that the complex between iproplatin and the organic bases of cytosine and thymine is the most stable state. This complex can be a suitable candidate for anticancer drugs based on the results obtained for each quantum chemical parameter from DFT computational studies. Substitution of either the coordinated chloride or aqua moeities was delved under mock first-order conditions as a function of attention and temperature. Experimental data were corroborated with DFT calculations. The kinetic and mechanistic study of the ligand negotiation responses of a series of transplatinum(II) complexes was performed.

A review on Bioimaging, Biosensing, and Drug Delivery Systems Based on Graphene Quantum Dots

Abdollah Khosravanian; Ahmad Moslehipour; Hossein Ashrafian

Volume 4, Issue 1 , January 2021, , Pages 44-56

https://doi.org/10.22034/pcbr.2020.237134.1102

Abstract

Graphene quantum dots (GQDs), which are the most capable carbon-based nanostructures, play a significant role in biological studies. These nanostructures show significant attributes ... Read More

Development and validation of RP-HPLC method for simultaneous quantification of the anticancer agents, nilotinib and sorafenib: Application in In-vitro analysis

Azra Takhvar; Somaye Akbari; Effat Souri; Reza Ahmadkhaniha; Ali Morsali; Mohammad Reza Khoshayand; Mohsen Amini

Volume 5, Issue 1 , February 2022, , Pages 44-52

https://doi.org/10.22034/pcbr.2022.319844.1204

Abstract

In this research, a reversed phase high performance liquid chromatographic method was developed for the simultaneous determination of two tyrosine kinase inhibitors, nilotinib and sorafenib. ... Read More

Theoretical studies of 2-[(E)-(3-phenylmethoxyphenyl) methylideneamino]guanidine as promising drugs against SARS-coronavirus spike glycoproteins by molecular docking combined with molecular dynamics simulation and MM/GBSA calculation

Emmanuel Israel Edache; Adamu Uzairu; Paul Andrew Mamza; Gideon Adamu Shallangwa

Volume 6, Issue 1 , January 2023, , Pages 46-60

https://doi.org/10.22034/pcbr.2023.370115.1237

Abstract

The novel 2-[(E)-(3-phenylmethoxyphenyl)methylideneamin-o]guanidine was put forth as a potential anti-SARS-coronavirus-2 candidate targeting the spike glycoprotein following a docking ... Read More

Heavy Metal Pollution in the Marine Environment: A Study Contribution of Three Rivers to the Pollution at the Upper of the River Niger, Nigeria

Tabugbo I Blessing; Okechukwu Josephat Ogbuagu; Uche Eunice Ekpunobi; Vincent Nwalieji Okafor; Usman Rilwan

Volume 7, Issue 1 , January 2024, , Pages 51-64

https://doi.org/10.48309/pcbr.2024.421932.1300

Abstract

Water is not only essential for life, but also it is life. Safeguarding this resource from heavy metals is good for our well-being. This research investigated heavy metals content and ... Read More

Removal of Copper II from Industrial Effluent with Beta Zeolite Nanocrystals

Bijan Ghanavati; Alireza Bozorgian

Volume 5, Issue 1 , February 2022, , Pages 53-67

https://doi.org/10.22034/pcbr.2022.328704.1213

Abstract

Heavy metals, including copper, are one of the most toxic pollutants in the world today due to the consumption prevalence in industry. There are several ways to remove copper ... Read More

One Pot Reductive Synthesis of Benzimidazole Derivatives from 2-Nitro Aniline and Aromatic Aldehydes Using Zn/NaHSO3 in Water Medium

Hridoydip Ranjan Dasgupta; Suvodip Mukherjee; pranab ghosh

Volume 4, Issue 1 , January 2021, , Pages 57-67

https://doi.org/10.22034/pcbr.2020.245413.1126

Abstract

Small amount of Zn dust and NaHSO3 was utilized to efficiently synthesize benzimidazole derivatives via one pot reductive cyclocondensation process in water medium at 100oC temperature. ... Read More

Volume 7 (2024)

Volume 6 (2023)

Volume 5 (2022)

Volume 4 (2021)

Volume 3 (2020)

Volume 2 (2019)

Volume 1 (2018)

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