TY - JOUR ID - 131795 TI - Bioactivity of Arachis hypogaea Shell Extracts against Staphylococcus aureus and Pseudomonas aeruginosa JO - Progress in Chemical and Biochemical Research JA - PCBR LA - en SN - 2676-7090 AU - Asemave, Kaana AD - Department of Chemistry, Benue State University, Nigeria Y1 - 2021 PY - 2021 VL - 4 IS - 3 SP - 331 EP - 336 KW - Sustainable feed-stock KW - Bioactivity KW - Staphylococcus aureus KW - Pseudomonas aeruginosa DO - 10.22034/pcbr.2021.290653.1190 N2 - Groundnut shells (GSs) are abundant renewable by-products which have been underexploited for potential applications. Therefore, this paper reports the bioactive potential of groundnut shell extracts (GSEs) against Staphylococcus aureus and Pseudomonas aeruginosa. The GSs were ground into powder form and subjected to extraction using ethanol, ethyl acetate, and a mixture of ethanol and ethyl acetate using an electrical shaker for 6 h and 12 h; and subsequently centrifuged at 2000 rpm for 20 min. The GSEs were then qualitatively screened for phenol, quinone, saponin tannins, and flavonoids using the standard procedures. More so, antibacterial activities of these GSEs against P. aeruginosa (ATCC 29953) and S. aureus (ATCC 25923) were tested using Agar well diffusion method on Mueller-Hinton agar (MHA). Therefore, the preliminary phytochemical screening reviewed the presence of saponin, tannin, flavonoid, quinone, and phenol. And the investigation of the antibacterial activities against Staphylococcus aureus and Pseudomonas aeruginosa demonstrated that S. aeureus was more sensitive to attack by the EtOH derived GSEs; whereas, P. aeruginosa was readily affected by the EtOAc GSEs. Generally, P. aeruginosa was more inhibited by these GSEs even at the lower concentrations of 25 and 12.5 mg/ mL; especially with the EtOH + EtOAc and EtOAc derived GSEs. EtOH + EtOAc GSE has potential of enhancing these bacterial inhibitions UR - https://www.pcbiochemres.com/article_131795.html L1 - https://www.pcbiochemres.com/article_131795_6334e4b3cb6e2a230c690e0aa7fcec53.pdf ER -