Sami Publishing CompanyProgress in Chemical and Biochemical Research2676-70901120181001Ultrasensitive and selective non-enzymatic glucose detection based on pt electrode modified by carbon nanotubes@ graphene oxide/ nickel hydroxide-Nafion hybrid composite in alkaline media1107412410.29088/SAMI/PCBR.2018.1.110ENSirous MohammadiDepartment of Chemistry, Islamic Azad University, Ilam branch, Ilam, IranAlireza TaheriDepartment of Chemistry, Islamic Azad University, Ilam branch, Ilam, Iran0000-0003-3113-2148Zeinab Rezayati-ZadDepartment of Food and Drug, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran0000-0001-9749-1915Journal Article20180909A new enzymeless glucose sensor has been fabricated and its electrocatalytic oxidation has been investigated in alkaline medium directly on the Pt Electrode modified by Activated carbon nanotubes @ graphene oxide/ nickel hydroxide-Nafion hybrid composite (PtACNT@GONHNPsNf). Under the optimized condition, the calibration curve is linear in the concentration range of 5-1100 µM using cyclic voltammetric method. The detection limit and sensitivity are 0.75 µM and 40 nA, respectively. The glucose sensor can be renewed easily in a reproducible manner by a simple polishing step and it has a long operational lifetime and short response time t90% < 1 s. In addition, the fabrication of Pt with nafion and nickel hydroxide powder was employed to eliminate the interference of ascorbic acid during the catalytic oxidation of glucose. The biosensor was used for determination of glucose in human blood serum and the oxidant with satisfactory results.Sami Publishing CompanyProgress in Chemical and Biochemical Research2676-70901120181001Cyclic Voltammetric studies of calcium acetate salt with Methylene blue (MB) Using Gold Electrode11187921710.29088/SAMI/PCBR.2018.1.1118ENM EldefrawyChemistry Department,Faculty of Science, Mansoura University, Mansoura, Egypt.Essamhassan G Arafa GomaaChemistry Department,Faculty of Science, Mansoura University, Mansoura, Egypt.Shereen SalemChemistry Department,Faculty of Science, Mansoura University, Mansoura, Egypt.Fatma Abdel RazikChemistry Department,Faculty of Science, Mansoura University, Mansoura, Egypt.Journal Article20181025Cyclic Voltammetric studies of calcium acetate salt [Ca(CH<sub>3</sub>COO)<sub>2</sub>] in absence or presence of Methylene blue (MB) were performed to predict and analyze the behavior of complexation between the ligand and metal ion in aqueous solution. From these studies, the values of solvation and kinetic parameters [E<sub>p </sub> (peak potential), Ip(peak current), ΔE<sub>p </sub> (peak potential difference), E<sub>½</sub> (half wave potential), D(Diffusion coefficient), K<sub>s</sub> (electron transfer rate constant), Г(surface coverage) and Q<sub>a</sub> (quantity of electricity)] were evaluated. In addition, the effect of different concentration and a scan rate of above the calculated quantities were studied. In case of presence MB, the stability constants and Gibbs free energies were performed.Sami Publishing CompanyProgress in Chemical and Biochemical Research2676-70901120181001Thermodynamic and Theoretical solvation parameters for 2-amino-4,5-dimethylthiophene-3-carboxamide(ADTC) in Ethanol and Mixed EtOH-H2O solvents19287943510.29088/SAMI/PCBR.2018.1.1928ENEssamhassan G Arafa GomaaChemistry Department, Faculty of Science, Mansoura University, 35516-Mansoura, EgyptMoged A. BerghoutChemistry Department, Faculty of Science, Mansoura University, 35516-Mansoura, EgyptMohamed R. MoustafaChemistry Department, Faculty of Science, Damietta University, Damietta, EgyptFathy M. El TaweelChemistry Department, Faculty of Science, Damietta University, Damietta, EgyptHader M . FaridChemistry Department, Faculty of Science, Mansoura University, 35516-Mansoura, EgyptChemistry Department, Faculty of Science, Damietta University, Damietta, EgyptJournal Article20181026The molar solubility for 2-amino-4,5-dimethylthiophene-3-carboxamide (ADTC) in pure ethanol and mixed ethanol (EtOH)- water solvents were measured at five different temperatures, 293.15, 298.15, 303.15, 308.15, and 313.15 K in the used mixed solvents, the solubility were increase by increase in the mole fraction of ethanol in the mixtures and increase of temperature due to more salvation parameters. All the solvation and thermodynamic parameters for ADTC in mixed EtOH+ H<sub>2</sub>O solvents were evaluated like solubility products, Gibbs free energies, enthalpies and entropies of solvation and discussed. Theoretical calculations for (ADTC) were done quantum mechanically by using Gaussian on set of calculations in ethanol for evaluating the different thermodynamic parameters.Sami Publishing CompanyProgress in Chemical and Biochemical Research2676-70901120181001Antiulcerogenic Activity of methanol extract and solvent fractions of Stem Bark of Lannea acida (A. Rich) Against Ethanol-Induced Gastric Mucosal Injury in Albino Rats29398078810.29088/SAMI/PCBR.2018.1.2939ENOnoshe SolomonDepartment of Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.Wasagu Rabiu Saidu UmarDepartment of Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.Hassan Sanusi WaraDepartment of Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.Abubakar Sadiq YakubuDepartment of Veterinary Medicine and Surgery, Usmanu Danfodiyo University, Sokoto, Nigeria.Madusolumou Michael AzubuikeDepartment of Biochemistry, School of Life sciences, Modibbo Adama University of Technology, Yola, Nigeria.Mbahi Asugu MaryDepartment of Biological Sciences, Federal University Kashere, Gombe, Nigeria.Hitler LouisCAS Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Centre for Excellence in Nanoscience, National Centre for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing 100191, China0000-0002-0286-2865Journal Article20181112Peptic ulcer disease is one of the most prevalent gastrointestinal disorders causing tremendous human suffering worldwide. The present study was designed to evaluate the antiulcerogenic activity of the methanol and solvent stem bark fractions (hexane, ethyl acetate and butanol) and elucidate their possible antiulcerogenic mechanisms. The antiulcerogenic mechanisms were investigated by estimation of Superoxide dismutase (SOD), Glutathione (GSH), Catalase (CAT), Vitamins A, C and E, Malondialdehyde (MDA) and involvement of K<sub>ATp </sub> channel. Pretreatment with the methanol extract and solvent fractions produce significant reductions in ulcer index in a dose dependent manner. Ethylacetate fraction (EtyAc) showed the highest antiulcer activity. Elevated MDA and decreased levels of SOD, GSH, CAT, Vitamin A, C and E observed in ulcer control groups were significantly decreased and increased respectively in the EtyAc fraction treated groups. Antiulcer activity of the EtyAc fraction was blocked upon coadministration with glibenclamide; a K<sub>ATp </sub> channel blocker. The stem bark extract of <em>Lannea acida</em> possess antiulcerogenic activity and the mechanisms seems to involve antioxidant activity and K<sub>ATp </sub> channel opening.Sami Publishing CompanyProgress in Chemical and Biochemical Research2676-70901120181001Reduced graphene oxide based on simultaneous detection of neurotransmitters40498140910.29088/SAMI/PCBR.2018.1.4049ENG. VinodhkumarDepartment of Physics, Raja Doraisingam Govt. Arts College, Sivaganga, India.R RamyaDepartment of Bioelectronics and Biosensors, Alagappa University, Karaikudi, India.Mark VimalanDepartment of Physics, Thirumalai Engineering College, Kilambi, Kancheepuram, IndiaI PotheherDepartment of Physics, Bharathidasan Institute of Technology (BIT) Campus, Anna University, Thiruchirappalli, India.A. Cyrac PeterDepartment of Physics, Raja Doraisingam Govt. Arts College, Sivaganga, India.Journal Article20181123Reduced graphene oxide (rGO) is synthesized using strong oxidizing agents with the help of chemical reduction method. Structural and physiochemical properties of the prepared sample are studied by ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD) and scanning electron microscopy (SEM). UV-Vis spectra of GO exhibit maximum absorption peak attributable to restoration of sp <sup>2</sup>carbon. Electrochemical study performed for bare and rGO modified glassy carbon electrode. Electrochemical sensing of Dopamine (DA) and Uric Acid (UA) was examined by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and square wave voltammetry (SWV) were conducted in phosphate buffer solution (PBS) at pH = 7.0 done for both simultaneous and individual determination of DA and UA in the range of 500nM – 1mM exhibit a wide linear range of detection and having low limit of detection (LOD) of 0.67µM for DA, and 0.69µM for UA estimated for simultaneous determination and in individual determination it was found to be 0.51µM and 0.42µM for DA and UA respectively. Additionally, the modified electrode exhibits good reproducibility, selectivity, sensitivity and stability. The proposed sensor could be applied for the determination of DA and UA in real samples.Sami Publishing CompanyProgress in Chemical and Biochemical Research2676-70901120181001Sorptive chelation of metals by inorganic functionalized organic WOx–EDA nanowires: adsorbent characterization and isotherm studies50598161710.29088/SAMI/PCBR.2018.1.5059ENAdams UdojiItodoDepartment of Chemistry, Federal University of Agriculture, PMB 2373 Makurdi, Nigeria0000-0002-4755-2270Ohemu Michael ItodoDepartment of Chemistry, Federal University of Agriculture, PMB 2373 Makurdi, NigeriaEsther IornumbeDepartment of Chemistry, Federal University of Agriculture, PMB 2373 Makurdi, NigeriaMichael Omotola FayomiDepartment of Chemistry, Federal University of Agriculture, PMB 2373 Makurdi, NigeriaJournal Article20181216<span style="font-size: 10.0pt; font-family: 'Cambria','serif'; mso-ascii-theme-font: major-latin; mso-fareast-font-family: 'Times New Roman'; mso-hansi-theme-font: major-latin; mso-bidi-font-family: 'Times New Roman'; color: #333333;" lang="EN-GB">Synthesis and Characterization of Inorganic–organic hybrid Tungsten oxide-ethylenediamine (WO<em>x</em>–EDA) nanowires have been carried out by a simple, low-cost and high-yield solvo-thermal method. The WO<em>x</em>–EDA nanowire adsorbent was characterized using, Fourier-transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Energy Dispersive X-ray spectroscopy (EDX). Adsorptive potential of the hybrid for aqueous phase copper and lead removal was investigated using batch adsorption process. The equilibrium data were subjected to various isotherm models. The Langmuir model shows high applicability (R<sup>2 </sup>of 0.921) for lead uptake. Other R<sup>2 </sup>values include 0.882 (for Freundlich model), 0.947 (Temkin) and 0.972 (Dubinin- Radushkevich). Similarly, adsorption experimental runs for Cu uptake gave correlation coefficient (R<sup>2</sup>) values of 0.972, 0.584, 0.906 and 0.899 for the Langmuir, Freundlich, Temkin and Dubinin- Radushkevich isotherm models respectively. Overall, Tungsten oxide ethylenediamine adsorbent proved its potential candidature for the chelating treatment of Pb and Cu poisoning as well as purifications of water containing such metals.</span><br /> <strong><span style="font-size: 14.0pt; font-family: 'Cambria','serif'; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin; mso-bidi-font-family: 'Times New Roman'; position: relative; top: -3.5pt; mso-text-raise: 3.5pt; mso-ansi-language: EN-US; mso-fareast-language: EN-GB;">Sorptive chelation of metals by inorganic functionalized organic WO<em>x</em>–EDA nanowires: adsorbent characterization and isotherm studies </span></strong>