Progress in Chemical and Biochemical Research

Review Article

Potential Plasma Biomarkers for Diagnosis of Alzheimer’s Disease: An Overview

AbdulBasit MustakAhamad Shaikh; Umesh Pravin Dhuldhaj

Volume 7, Issue 2 , May 2024, Pages 114-128

https://doi.org/10.48309/pcbr.2024.413416.1285

Abstract

Alzheimer’s disease (AD) is the widely known neuro-degenerative disease, responsible for cognitive decline and progressive memory loss, results from the brain shrinkage (called ... Read More

Review Article

Cyanoacrylate Chemistry and Polymerization Mechanisms

Humphrey Sam Samuel; Ugo Nweke-Maraizu; Emmanuel E Etim

Volume 7, Issue 2 , May 2024, Pages 129-142

https://doi.org/10.48309/pcbr.2024.422869.1304

Abstract

Cyanoacrylates have gained widespread attention and found applications across various industries due to their exceptional bonding capabilities. This study delves into the fundamental ... Read More

Original Research Article

Furan and Phenol-Based Contaminants in the Borehole Water Quality of the Kerio Valley Water Basin, Kenya

Festus Kipkemoi Langat; Joshua Kibet; Francis Okanga

Volume 7, Issue 2 , May 2024, Pages 143-153

https://doi.org/10.48309/pcbr.2024.427199.1322

Abstract

Clean water supply and infrastructure is one of the greatest challenges of the 21st century as a result of persistent and emerging water pollutants. The purpose ... Read More

Review Article

The Impact of Administering (S)-4-[1-(2, 3-dimethylphenyl) ethyl]-1H-imidazole (Dexmedetomidine) During Surgery on Immediate and Long-Term Pain after Simple Mastectomy: A Systematic Review

Ali Sharifi; Fariborz Rousta

Volume 7, Issue 2 , May 2024, Pages 154-167

https://doi.org/10.48309/pcbr.2024.424520.1312

Abstract

Introduction: This systematic review will evaluate the impact of administering dexmedetomidine during surgery on immediate and long-term pain outcomes after simple mastectomy. By synthesizing ... Read More Introduction: This systematic review will evaluate the impact of administering dexmedetomidine during surgery on immediate and long-term pain outcomes after simple mastectomy. By synthesizing the available evidence, the review aims to provide a comprehensive understanding of the potential benefits of (S)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole: dexmedetomidine in this specific surgical context and inform clinical practice.Material and Methods: An extensive exploration of electronic databases, specifically PubMed, Embase, and the Cochrane Library, was undertaken to pinpoint pertinent studies (during 2000-2023). The search methodology encompassed a fusion of medical subject headings (MeSH) terms and keywords pertinent to "dexmedetomidine," "mastectomy"," Simple Mastectomy" and "postoperative pain." The search was confined to studies available in the English language. Moreover, the reference lists of identified articles and conference proceedings underwent manual scrutiny to unearth any supplementary studies of relevance.Results: Regarding postoperative pain intensity, the majority of studies reported significantly lower pain scores in the (S)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole: dexmedetomidine group compared to the control group at various time points during the immediate postoperative period(p˂0.05). (S)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole: dexmedetomidine infusion was associated with reduced pain intensity(p˂0.05), both at rest and with movement(p˃0.05), indicating improved analgesia(p˂0.05).Conclusion: Administering (S)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole: dexmedetomidine during surgery for simple mastectomy may have a positive impact on immediate and long-term pain outcomes. (S)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole: dexmedetomidine infusion is associated with reduced postoperative pain intensity, decreased opioid consumption, prolonged duration of analgesia, and improved patient satisfaction.Material: A narrative synthesis of the included studies will be conducted to summarize the characteristics, interventions, and outcomes of the studies. The findings will be presented in a tabular format. If deemed appropriate and feasible, a meta-analysis will be performed to calculate pooled effect sizes using appropriate statistical methods (Mantel-Haenszel or inverse variance methods) for the primary outcome measures.Results:The majority of the included studies reported postoperative pain scores as an outcome measure. The findings consistently demonstrated that both acetaminophen and NSAIDs were effective in reducing postoperative pain after esophagectomy. However, no significant differences were observed between the two analgesic options in terms of pain scores. Both groups showed comparable pain relief during the immediate postoperative period.Conclusion: based on the available evidence, both acetaminophen and NSAIDs are effective options for postoperative pain management after esophagectomy. Both analgesics demonstrate comparable efficacy in alleviating pain, reducing opioid consumption, prolonging the time to first analgesic request, and ensuring patient satisfaction. The decision regarding the choice of analgesic should consider individual patient characteristics, comorbidities, and potential adverse effects.

Review Article

Platelet-Rich Plasma Effect in Femoral Head Osteotomy Outcome: A Systematic Review

Mohammad Irajian; Parham Maroufi

Volume 7, Issue 2 , May 2024, Pages 168-181

https://doi.org/10.48309/pcbr.2023.424490.1310

Abstract

Introduction: This systematic review seeks to assess the impact of platelet-rich plasma (PRP) on the outcomes of femoral head osteotomy and aims to evaluate platelet-rich plasma effect ... Read More

Original Research Article

Evaluation of Hot Corrosion of Hot Dip Aluminized Coated Superalloy IN738LC in Melted Na2SO4-25wt% NaCl Salt

Mohammad Sajjadnejad; Vahid Tavakoli Targhi; Seyyed Mohammad Saleh Haghshenas

Volume 7, Issue 2 , May 2024, Pages 182-197

https://doi.org/10.48309/pcbr.2024.432210.1331

Abstract

Superalloy IN738LC is categorized as one of the most frequently utilized nickel base superalloys in the production of hot section components due to its multiphase microstructure maximizing ... Read More

View Article

Review Article

Emerging Co-Cultivation Strategies for Microalgal Biomass and Biodiesel Production

Merit Oluchi Ori; Francis-Dominic Makong Ekpan; Humphrey Sam Samuel; Odii Peter Egwuatu

Volume 7, Issue 2 , May 2024, Pages 198-224

https://doi.org/10.48309/pcbr.2024.425990.1317

Abstract

Microalgae have garnered significant attention as a promising source for biodiesel production due to their rapid growth, high lipid content, and minimal resource requirements. This ... Read More

View Article

Progress in Chemical and Biochemical Research

Articles in Press

Current Issue

Volume 7 (2024)

Volume 6 (2023)

Volume 5 (2022)

Volume 4 (2021)

Volume 3 (2020)

Volume 2 (2019)

Volume 1 (2018)

Volume & Issue: Volume 7, Issue 2, May 2024, Pages 114-224

Potential Plasma Biomarkers for Diagnosis of Alzheimer’s Disease: An Overview

Abstract

Cyanoacrylate Chemistry and Polymerization Mechanisms

Abstract

Furan and Phenol-Based Contaminants in the Borehole Water Quality of the Kerio Valley Water Basin, Kenya

Abstract

The Impact of Administering (S)-4-[1-(2, 3-dimethylphenyl) ethyl]-1H-imidazole (Dexmedetomidine) During Surgery on Immediate and Long-Term Pain after Simple Mastectomy: A Systematic Review

Abstract

Platelet-Rich Plasma Effect in Femoral Head Osteotomy Outcome: A Systematic Review

Abstract

Evaluation of Hot Corrosion of Hot Dip Aluminized Coated Superalloy IN738LC in Melted Na2SO4-25wt% NaCl Salt

Abstract

Emerging Co-Cultivation Strategies for Microalgal Biomass and Biodiesel Production

Abstract